ABSTRACT
Se presenta el caso de un recién nacido pretérmino de 34 semanas de edad gestacional y cuya madre inicia con picos febriles de hasta 39§C 72 horas antes del nacimiento, así como con datos de actividad uterina. Se corrobora infección de vías urinarias, por lo que se hospitaliza e inicia manejo con cefalosporinas de segunda generación, así como uteroinhibidores. La evolución es incidiosa, y debido a la presencia de datos de sufrimiento fetal se realiza cesárea urgente; se observa salida de líquido meconial +++. El producto nace con apnea primaria y muere a las siete horas de vida extrauterina. El estudio histopatológico demostró la presencia de microabscesos y granulomas diseminados, lo que se corrobora en la mayoría de los órganos con las manifestaciones clínicas de listeria temprana, conocido como síndrome de granulomatosis infantiséptica
Subject(s)
Humans , Infant, Newborn , Infant Mortality , Listeria , Listeriosis/mortality , Listeriosis/pathology , Wounds and Injuries/physiopathologyABSTRACT
The rate of listeria abortion in Tehran was investigated, Abortion samples [200] were cold enriched at 4°C and subcultured on selective culture media containing acriflavin, nalidixic acid and potassium thiocyanate. Sera of patients were tested serologically [IF method] for screening, and results were confirmed by culturing the positive samples. Antibody against L. monocytogenes was obtained in 70.7% of sera but the bacteria was isolated from five samples only
Subject(s)
Humans , Female , Listeriosis/mortality , Abortion/etiology , Listeria/pathogenicityABSTRACT
OBJECTIVE--to verify the effects of Listeria monocytogenes (LM) inoculation in the survival of animals bearing Ehrlich's tumor. KIND OF STUDY--experimental. Animals-isogenic mice, Balb/c, female, 19-21 g. Tumor-Ascitic Ehrlich's tumor, dilution of 5 x 10(5) cells/0.1 ml. Bacteria-LM serotype 4a, solution with 7 x 10(3) bacteria (standard sub-lethal dose). Intervention-a) inoculation of LM in mice bearing Ehrlich tumor at the same time as ascitic cells transplantation. b) inoculation of LM seven days before and, again, seven and fourteen days after ascitic cells transplantation. c) to study the effect of using ampicillin 100 mg/kg, im, simultaneously with the inoculation of Ehrlich tumor and LM organisms and, again, 3, 5, 7, 14, 21 and 30 days after the ascitic cells transplantation. ANALYSIS--Chi-square test; p < 0.05 RESULTS AND CONCLUSION--LM increases significantly the survival of mice bearing Ehrlich tumor even when only one inoculum of viable LM was used, seven days before or seven days after the ascitic cells transplantation. The use of ampicillin after the inoculation of LM and tumor transplantation does not alter the survival of mice